当前位置: 首页» 科学研究» 研究中心

动物基因组研究中心

来源: 发布者: 时间:2020年02月10日

  动物基因组研究中心

  Research Center for AnimalGenomics

  

  人员组成 / Personnel Structure

  动物基因组研究中心现有中国农科院创新团队3个、课题组6个,国家重大人才计划入选者3人,深圳市国家级领军人才1名,深圳市海外高层次人才4名,中心现有成员共计54人,其中博士生导师6名,研究员6名,博士后9名,研究生21名。

  The center consists of two innovation groups of CAAS and four labs. Among the 54 team members, one person awarded “National Thousand Talent Program”, three have received the National Key Project Fund from NSFC, one have received the National Leading Personnel in Shenzhen, and four have received the Overseas High-level Talents in Shenzhen. The team includes six doctoral advisors, six research professors, and nine post-doctoral, 21 graduate students.

  

  研究方向 / Research Areas

  (1)利用多元组学整合手段,解析猪等动物的经济性状形成遗传基础和挖掘重要候选基因和分子标记;

         Integrate multi-omics methods to understand the genetic basis of economic traits of pigs and other livestock animals and identify important candidate genes and molecular marks for genetic breeding;

  (2)发展全基因组选择和基因组编辑技术,开展猪的遗传改良和种质创新,创制医用重要疾病模型猪;

         Develop genomic selection and genome editing technologies, carry out breed innovation and genetic improvement in pigs, and create disease model pigs for medical research;

  (3)构建脊椎动物的三维转录调控网络,大规模筛选并验证转录调控元件,阐明关键基因和非编码RNA功能;

           Construct three-dimensional transcriptional regulatory networks of vertebrates, screen for and verify transcriptional regulatory elements on a large scale, and elucidate the functions of key genes and non-coding RNAs;

  (4)构筑仔猪营养、微生物与表观基因组研究模型系统,解析菌群、营养素等环境因子对动物发育与疾病发生的表观遗传效应;

          Construct model systems for piglet nutrition, microbial and epigenomics research; analyze the epigenetic effects of environmental factors such as flora and nutrients on animal development and disease;

  (5)开发基因溯源等技术体系,保障动物源性食品安全。

          Develop technology systems, such as DNA tracing to ensure animal-derived food safety.

 

  

  任务目标 / Objectives

  动物基因组研究中心将综合运用多组学技术、基因组选择和基因组编辑等手段,阐明猪等动物重要组织器官发育和经济性状形成的遗传和表观遗传机理;开展猪等动物的遗传改良和种质创新,为畜牧生产提供优良种质;研究环境因子对动物的表观遗传效应;解决畜牧业可持续发展中的遗传育种关键问题,并为人类医学研究提供动物模型。此外,中心将开发基因溯源技术,为粤港澳大湾区的动物源性食品安全提供保障。

  The Animal Genome Research Center will use multi-omics techniques, genome selection and genome editing to elucidate the genetic and epigenetic mechanisms underlying the development of important organs and economic traits in pigs and other animals; Develop genetic improvement and carry out new material creation and breed improvement in pigs and other livestock animals; Study the epigenetic effects of environmental factors on animals; Solve the key problems of genetic breeding in the sustainable development of pig industry, and provide animal models for human medical research. In addition, the Center will develop DNA tracing technology to ensure the quality and safety of food of animal originin the Guangdong-Hong Kong-Macau Greater Bay Area.

   

  良猪计划 / A+ Pig Program (APP)

  我国是世界上最大的生猪养殖和猪肉消费国。“良猪计划”主要针对优良种猪培育和猪肉产品安全等两大产业问题,以组学技术为核心,围绕“良种猪、放心肉”两个目标,实现优良种猪国产化、生猪及产品的精准溯源,为我国生猪养殖可持续发展和猪肉食品安全提供保障。通过项目实施,将在猪重要经济性状形成机制的理论上取得重大突破,建立全基因组选择和基因组编辑两大技术体系,实现对每头生猪及产品的精准溯源。

  China is the world's largest pig farming and pork consumer. The “A+ Pig Program” is mainly aimed at the two major industrial issues of excellent breeding pig breeding and pork product safety. With the core of Omics technology, it focuses on the two goals of “great breeding pigs and safety pork” to achieve the localization of fine breeding pigs and the precision of pigs and products Tracing to the source provides a guarantee for the sustainable development of pig farming and pork food safety in China. Through the implementation of the project, major breakthroughs will be made in the theory of the important economic trait formation mechanism of pigs. Established two major technical systems for whole genome selection and genome editing to achieve precise traceability for each pig and product.

  

  创新团队 / Innovation groups of CAAS

  猪基因组设计育种创新团队

  Pig genome design and breeding innovation team

  动物功能基因组学创新团队

  Animal Functional Genomics Innovation Team

  农业表观基因组学创新团队

  Agricultural Epigenomics Group (AEG)

  

  课题组 / Labs

  唐中林课题组 / Tang Zhonglin Lab

  左二伟课题组 / Zuo Erwei Lab

  Yuwen Liu课题组 / Liu Yuwen Lab

  易国强课题组 / Yi Guoqiang Lab

  Zhang Yubo 课题组 / Zhang Yubo Lab

  高  飞课题组 / Gao Fei Lab

【打印】 【关闭】