汪泉课题组

汪泉课题组

Wangquan Lab

课题组长

汪泉，研究员，博士生导师。

主要研究领域为植物发育生物学。研究成果在Molecular Plant，Plant Cell、JIPB、New Phytologist和Plant Journal等著名学术期刊发表。

研究内容

植物一生中不断产生新器官，而新器官的形成会伴随边界区域（Boundary）的产生。边界区域不仅将植物新旧器官区分开来，也可能是新的器官或组织起始的区域。因此，边界区域的产生对器官发生至关重要。此外，边界区域也会在器官内部出现，参与器官的形态建成和特化。水稻在整个生命周期也伴随着不同的边界区域的产生，这些边界区域可影响多个重要农艺性状。1. 营养生长期，叶原基与顶端分生组织之间的传统边界区域，影响叶及分蘖等；2. 叶发育后，叶枕区的形成（叶片和叶鞘连接区），影响叶夹角等；3. 水稻节建成及节间伸长，影响株高等；4. 离层发育，影响落粒性等。通过对水稻不同边界区域形成的分子机制的研究，可以加深对植物器官发生的理解，同时还能够为生产实践中培育优良品种提供知识储备和重要的遗传材料。

研究进展

1. 前期通过全基因组关联分析及遗传学验证，表明赤霉素对水稻的落粒性也有重要调控作用。赤霉素信号的重要抑制因子SLR1可与落粒性重要调控因子qSH1，SHAT1和SNB互作，影响离层区域木质素积累，从而调控水稻落粒性。

2. 水稻节的建成和节间伸长也依赖于边界区域相关基因。研究表明，调控叶极性建成相关的OsKANADI1、OsYABBY5等基因也控制节发育。OsKAN1、OsYAB5及OsGA2ox6通过调节茎部节间赤霉素含量进而影响水稻株高和节间伸长。

3. 边界区域的发育在物种间存在保守的调控机制，同一物种的不同边界区域也有主效的调控因子。前期通过突变体筛选获得了一株株高、叶形、分蘖异常的突变体。结合遗传学、组织学、分子生物学等手段，发现该突变体发育缺陷是由于一个保守的NAC转录因子OsCUC1突变引起的。OsCUC1在水稻中通过调控不同的下游基因来分别控制叶形、分蘖等发育。

代表论文

1. Zeyu Li#, Suikang Wang#, Longjun Zeng#, Wanshun Zhong, Ruoshu Yang, Guangzhong Zhang, Bing He, Tao Wang, Zhiqiang Liao, Yong Zhang, Peng Cui, Fang Yang, Guosheng Xiong, Qian Qian and Quan Wang*. A conserved boundary specific NAC transcription factor targets various regulators to modulate rice aerial architecture. Plant Cell. 2026, https://doi.org/10.1093/plcell/koag152.

2. Guangzhong Zhang#, Zeyu Li#, Shujing Kang#, Chang Tian, Longjun Zeng, Tao Huang, Yiqing Tan, Fenglin Su, Quan Wang*, Suikang Wang*. The microRNA399-PHOSPHATE2 module acts as a dual regulator of root architecture and systemic signaling under phosphate starvation in rice. The Crop Journal. 2026, https://doi.org/10.1016/j.cj.2026.06.003. (Co-corresponding)

3. Kai Hong, Xueying Yang, Yiqing Tan, Yonggang Liu, Qianwei Xia, Longjun Zeng, Linyuan Zou, Ke Wan, Ya Zhang, Shujing Kang, Tao Huang, Wanqing Lv, Ruicai Jia, Yi Wei, Quanyan Chen, Yankai Wang, Yonghui Zhao, Yaxing Wu, Jiudeng Yu, Hao Zhang, Bing Wang, Jijun Yan, Jinfang Chu, Xu Tang, Yong Zhang, Marcel Bucher, Yonghong Wang, Li Xue*, Quan Wang*, Jiayang Li, Guosheng Xiong*. Presymbiotic activation of karrikin signaling creates a permissive state for arbuscular mycorrhizal symbiosis by derepressing the NSP1-NSP2-SLR1 transcriptional complex in rice. Molecular Plant. 2026; 19(4):844-867. (Co-corresponding)

4. Chang Tian, Xu Tang, Guangzhong Zhang, Rui Zhang, Xinruolan Yang, Caiyun Yin, Hongfei Lin, Fenglin Su, Suikang Wang, Xiaoxia Li, Lianguang Shang, Yong Zhang*, Quan Wang*. Traits improvement of wild rice O. rufipogon via multiplex genome editing. Journal of Integrative Plant Biology. 2026; 68(1):20-22.

5. Minghao Liu, Guangzhong Zhang, Longjun Zeng, Jijun Yan, Peiyong Xin, Jinfang Chu, Quan Wang*, Suikang Wang*. Pathogen-Induced Endogenous Small Peptide Phytosulfokine Perceived by the Membrane Receptor OsPSKR2 Enhances Disease Resistance in Rice. Plant Cell & Environment. 2025; https://doi.org/10.1111/pce.70324. (Co-corresponding)

6. Zeyu Li, Shuyi He, Longjun Zeng, Guangzhong Zhang, Quan Wang*. The C2H2 Zinc-Finger protein ELR1 negatively regulates cytokinin metabolism and signaling pathway in rice. Functional & Integrative Genomics. 2025; https://doi.org/10.1007/s10142-025-01772-1

7. Jianping Zhou#, Rui Pang#, Yangshuo Han#, Yachong Guo, Yibo Wang, Hongjun Yang, Wei Wang, Xinxuan Fu, Rui Zhang, Xuelian Zheng, Tao Zhang*, Yong Zhang *, Quan Wang*. CRISPR-Cas9-Mediated Knockout of OsKCS11 in Rice Reveals Potential Crosstalk Between Very Long-Chain Fatty Acids and Cytokinin. Plant Journal. 2025; 122: e70208. (Co-corresponding)

8. Shujing Kang, Zeyu Li, Guangzhong Zhang, Yuexing Wang, Quan Wang*, Suikang Wang*. Auxin biosynthesis is required for phosphorus deficiency- induced root system architecture remodeling in rice. Physiologia Plantarum, 177: e70307. (Co-corresponding)

9. Qi He, Hao Wu, Longjun Zeng, Caiyun Yin, Li Wang, Yiqing Tan, Wanqing Lv, Zhiqiang Liao, Xuelian Zheng, Shuting Zhang, Qinqin Han, Danning Wang, Yong Zhang, Guosheng Xiong*, Quan Wang*, OsKANADI1 and OsYABBY5 regulate rice plant height by targeting GIBERELLIN 2-OXIDASE6. Plant Cell. 2025;37(1).

10. Hao Wu, Qi He, Bing He, Shuyi He, Longjun Zeng, Longbo Yang, Hong Zhang, Zhaoran Wei, Xingming Hu, Jiang Hu, Yong Zhang, Lianguang Shang, Suikang Wang, Peng Cui, Guosheng Xiong, Qian Qian, Quan Wang*. Gibberellin signaling regulates lignin biosynthesis to modulate rice seed shattering. Plant Cell. 2023; 35(12):4383-4404.

11. Tao Wang, Lijuan Lou, Zeyu Li, Lianguang Shang, Quan Wang*. Cloning and Characterization of Protein Prenyltransferase Alpha Subunit in Rice. Rice Science. 2021; 28(6): 557-566.

12. Fan Wu, Xinyu Qiao, Yafei Zhao, Ziyi Zhang, Yifan Gao, Lingfeng Shi, Haokun Du, Lulu Wang, Ya-Jie Zhang, Yu Zhang, Langyu Liu*, Quan Wang*, Dejing Kong*. Targeted Mutagenesis in Arabidopsis thaliana using CRISPR-Cas12b/C2c1. Journal of Integrative Plant Biology. 2020; 62(11):1653-1658. (Co-corresponding)

13. Quan Wang, Alice Hasson, Susanne Rossmann, Klaus Theres. Divide et Impera: Boundaries Shape the Plant Body and Initiate New Meristems. New Phytologist. 2016; 209(2):485-98.

14. Quan Wang, Wouter Kohlen, Susanne Rossmann, Teva Vernoux, Klaus Theres. Auxin Depletion from the Leaf Axil Conditions Competence for Axillary Meristem Formation in Arabidopsis and Tomato. Plant Cell. 2014; 26(5):2068-2079. Highlighted in the same issue, The Importance of Being Absent: Auxin Minima Are Required for Axillary Meristem Formation, Plant Cell. 26(5):1836.

15. Fang Yang#, Quan Wang#, Gregor Schmitz, Dörte Müller, Klaus Theres. The bHLH Protein ROX Acts in Concert with RAX1 and LAS to Modulate Axillary Meristem Formation in Arabidopsis. Plant Journal. 2012; 71(1):61-70.

汪泉课题组更新于2026年7月